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KMID : 0984920130150010048
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Journal of Skin Barrier Research
2013 Volume.15 No. 1 p.48 ~ p.58
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Recent Advance in the Skin Barrier Research from 2012 to the First Half of 2013
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Hong Seung-Phil
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Abstract
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Apart from classic stratum corneum components, the current field of research for skin barrier has become very diverse and extended which now includes studies of tight junction barrier called the liquid - liquid barrier, the interaction between innate barrier function and immunologic responses, and genetic issues for epidermal development and differentiation. In addition to the classic x-ray diffraction for investigating lipid organization and the array to knockout mouse model for revealing the role of specific gene, a diversity of the latest research methods have been introduced. It may be impossible to keep up all of these trends, but reviewing overall trends and notable studies may be helpful for both basic researchers and related industries. For this purpose, this review highlights some of the research advances in the skin barrier and atopic dermatitis that were reported from 2012 up to date in Pubmed.
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KEYWORD
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Atopic Dermatitis, Epidermal permeability barrier' Skin barrier research
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